Liza Lapira was born in Queens, New York and she moved to Los Angeles, California in 2004. She is of Filipino descent.
Liza Lapira's New York stage credits include As You Like It, The School for Wives, The Odyssey, and Alexandra Cunningham's No. 11 Blue and White. Liza Lapira's first major role was a series regular spot on the Showtime TV series Huff. Most recently, Liza Lapira played neuroscientist Ivy in both seasons of Joss Whedon's series Dollhouse, appearing predominantly with Fran Kranz and Dichen Lachman. Her TV credits include recurring roles in Dexter, NCIS, ER, Monk, Grey's Anatomy, Law & Order: SVU, The Parkers as Shaquan, Sex and the City, and The Sopranos.
Early film credits include director Tony Scott's Domino and independent feature The Big Bad Swim, which premiered at the Tribeca Film Festival in 2006, Liza Lapira appeared in J. J. Abrams' 2008 film Cloverfield as Heather and has a role in the films Table for Three and 21. In 2009, she played Agent Sophie Trinh in the film Fast & Furious opposite Paul Walker, and in 2010, she played Alva in Repo Men.
She was a cast member of the Fox series Traffic Light, and played Liz in the film Crazy, Stupid, Love., starring Steve Carell and Ryan Gosling.